A field experiment was conducted during rabi, 2014-15 at S.V. Agricultural College Farm, Tirupati to find out the response of quality protein maize hybrid (HQPM-1) to various N and S levels. The treatments consisted of four nitrogen levels (60, 120, 180, 240 kg N ha-1) in combination with three sulphur levels (15, 30, 45 kg S ha-1). The results of the experiment revealed that among the four nitrogen levels, application of 240 kg N ha-1 recorded the maximum cob length, cob girth, number of rows cob-1, number of grains row-1, grain weight cob-1, test weight, grain yield (5101 kg ha-1), stover yield (5569 kg ha-1) and harvest index (47.79 %) followed by 180, 120 and 60 kg N ha-1. Similarly, application of 45 kg S ha-1 resulted in significantly more cob length, cob girth, number of rows cob-1, number of grains row-1, grain weight cob-1, test weight, grain yield (3679 kg ha-1), stover yield (4029 kg ha-1) and harvest index (47.28 %) followed by lower levels of sulphur. Hence, N and S can be applied at the rate of 240 kg ha-1 and 45 kg ha-1, respectively to obtain higher yield.